Support & Solvents
Injection Kit
50 syringes + 100 padsEverything required to safely reconstitute and inject reconstituted peptides — 50 sterile insulin syringes plus 100 alcohol prep pads.
$25
Lyophilized · 5 mg / vial
Healing & Recovery
5 mg / vial
TB-500 5mg (Thymosin Beta-4 Fragment)
Tβ4 active fragment · Actin sequestration · Cellular migration · Recovery
Premium Grade
Synthetic version of the active region of naturally-occurring 43 amino acid Thymosin Beta-4.
- CAS Number
- 885340-08-9
- Molecular Weight
- 4 963 Da
- Purity
- ≥ 99.0% (HPLC)
- Storage
- −20 °C, lyophilized
Amino Acid Sequence
Ac-SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES
Free over $59$7.99 to US (48h) · $14.99 worldwide (5 business days)
Discreet PackagingPlain insulated mailer, no compound name on the outside.
Certificate of Analysis
Per-lot analytical report — HPLC, ESI-MS, LAL endotoxin, heavy metals, sterility
Current lotTBM101
Released2026-04-27
HPLC purity99.29%
Endotoxin (LAL)Pass · < 0.5 EU/mg
About TB-500 (Thymosin β-4 Fragment)
Buy TB-500 5mg at IGF1 Shop. TB-500 is a synthetic fragment (amino acids 17-23 + flanking residues) of the naturally occurring 43-amino-acid protein Thymosin Beta-4 (Tβ4). Each TB-500 5mg vial is HPLC ≥99% pure, identity-confirmed by ESI mass spectrometry, and tested for endotoxins below 0.5 EU/mg by LAL assay. TB-500 is widely discussed in the recovery space for its roles in actin binding, cellular migration, angiogenesis, and tissue regeneration. CAS 885340-08-9.
Also known as: TB-500 · TB 500 · Thymosin Beta-4 · Thymosin β-4 · Tβ4 fragment
TB-500 (Thymosin β-4 Fragment) — Mechanism & Specifications
TB-500 is the active fragment of Thymosin Beta-4, a 43-amino acid peptide present in virtually all human and animal cells. Research has investigated its role in actin sequestration, cell migration, angiogenesis and wound healing across muscle, tendon and cardiac tissue.
Quality & release criteria
Every lot of TB-500 (Thymosin β-4 Fragment) is released only after passing reverse-phase HPLC (≥ 99% area purity at 220 nm against a reference standard), ESI mass spectrometry confirmation of molecular weight, and Limulus Amebocyte Lysate (LAL) endotoxin testing below 0.5 EU/mg. The lot-specific Certificate of Analysis is provided with the order and available on request before purchase.
$66
3 vials · $22/vial
FAQ
TB-500 (Thymosin β-4 Fragment) — Frequently asked questions
What is TB-500?
TB-500 is a synthetic fragment of the naturally occurring protein Thymosin Beta-4 (Tβ4). It is a small, water-soluble peptide widely studied for its role in actin binding, cellular migration, and tissue regeneration. Each IGF1 Shop vial contains 5mg of pure TB-500 in lyophilized form (CAS 885340-08-9). The peptide is sealed under inert gas to preserve activity until reconstitution.
How pure is your TB-500?
Every batch of TB-500 is independently verified at ≥99% purity by reversed-phase HPLC, with molecular identity confirmed by ESI mass spectrometry. We also run LAL endotoxin testing with a release limit of <0.5 EU/mg and full sterility checks. The corresponding Certificate of Analysis (COA) for your exact lot is downloadable from the product page. All testing is performed at ISO 17025-accredited laboratories.
What is the typical TB-500 dose at 5mg?
Most reference protocols describe a two-phase approach: a loading phase of 4-8mg per week split across two injections for the first 4-6 weeks, followed by a maintenance dose of 2-4mg every 1-2 weeks. A single TB-500 5mg vial reconstituted with 2.5mL bacteriostatic water yields 2mg per 0.1mL. Always work from your reconstitution math, not assumptions. Cycle length depends entirely on personal goals.
How do I reconstitute TB-500 5mg?
Add 2-3mL of bacteriostatic water slowly down the side of the vial — do not aim the stream at the powder cake. Swirl gently until fully dissolved; do not shake. Once reconstituted, store TB-500 at 2-8°C and use within 30 days for best stability. Keep the unmixed vial at -20°C in a dry, dark place where it remains stable for up to 24 months.
How does TB-500 compare to BPC-157?
They target different stages of the repair cascade. BPC-157 is a 15-amino-acid gastric peptide that supports vascular signaling and early-phase tissue knitting. TB-500 drives actin polymerization, cellular migration, and angiogenesis at the structural-remodeling stage. Many users run them together — see our BPC-157 + TB-500 blend.
How long does TB-500 take to work?
Reported timelines in user logs vary widely. Acute soft-tissue programs typically run 4-6 weeks of loading before tapering. Chronic or stubborn complaints are often run for 8-12 weeks. Individual response depends on age, baseline tissue status, and the rest of your recovery stack.
Do you ship TB-500 internationally and discreetly?
Yes. We ship TB-500 worldwide in plain, unbranded packaging with no peptide-related markings on the outer label. Domestic and international tracking are provided. Orders above $59 ship free. We accept Bitcoin, USDT, Monero, and major cards, and the merchant descriptor on card statements is generic.
Is the COA tied to my exact vial?
Yes — every TB-500 vial carries a batch number that maps to a specific HPLC, mass-spec, and endotoxin report dated within the synthesis cycle of that lot. You can pull the PDF directly from the product page. We never reuse a previous lot's COA for a new synthesis run.
