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Lyophilized · 10 mg / vial SNAP-8 10 mg / vial — HPLC-verified peptide vial
Skin & Cosmetic 10 mg / vial

SNAP-8 10mg — Acetyl Octapeptide-3

Competitive SNAP-25 mimetic · SNARE-complex modulator · Cosmetic anti-wrinkle

Premium Grade

Acetyl octapeptide-3 — competitive SNAP-25 mimetic for SNARE-complex modulation in cosmetic anti-wrinkle pathways.

CAS Number
868844-74-0
Molecular Weight
888.0 Da
Purity
≥ 99.0% (HPLC)
Storage
−20 °C, lyophilized
Amino Acid Sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
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You pay today $54 3 vials · $18/vial
Free over $59$7.99 to US (48h) · $14.99 worldwide (5 business days)
Discreet PackagingPlain insulated mailer, no compound name on the outside.

Certificate of Analysis

Per-lot analytical report — HPLC, ESI-MS, LAL endotoxin, heavy metals, sterility

Current lotSNA690
Released2026-04-19
HPLC purity99.69%
Endotoxin (LAL)Pass · < 0.5 EU/mg

About SNAP-8

Buy SNAP-8 10mg at IGF1 Shop. SNAP-8 is a synthetic acetyl octapeptide (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2) that competitively inhibits SNAP-25 in the SNARE complex, modulating exocytosis at the neuromuscular junction. It is the principal active in many cosmetic anti-wrinkle topicals as a botulinum-toxin-like mechanism without the toxin itself. Each SNAP-8 10mg vial is HPLC ≥99% pure, identity-confirmed by ESI mass spectrometry, and accompanied by a per-lot Certificate of Analysis. CAS 868844-74-0.

Also known as: SNAP-8 · Acetyl Octapeptide-3 · Argireline analog · Anti-wrinkle peptide

SNAP-8 — Mechanism & Specifications

SNAP-8 is a synthetic acetyl octapeptide that competitively inhibits SNAP-25 in the SNARE complex, modulating exocytosis at the neuromuscular junction. Used in topical and dermal applications as a botulinum-toxin-like mechanism of action without the toxin itself.

Quality & release criteria

Every lot of SNAP-8 is released only after passing reverse-phase HPLC (≥ 99% area purity at 220 nm against a reference standard), ESI mass spectrometry confirmation of molecular weight, and Limulus Amebocyte Lysate (LAL) endotoxin testing below 0.5 EU/mg. The lot-specific Certificate of Analysis is provided with the order and available on request before purchase.

FAQ

SNAP-8 — Frequently asked questions

What is SNAP-8?
SNAP-8 (Acetyl Octapeptide-3) is a synthetic acetyl octapeptide that competitively inhibits SNAP-25 in the SNARE complex, modulating exocytosis at the neuromuscular junction. It is widely used in topical anti-wrinkle cosmetics as a botulinum-toxin-like mechanism without the toxin itself. CAS 868844-74-0.
How is SNAP-8 typically used?
SNAP-8 is typically formulated into topical serums at 3-10% concentration applied to expression-line areas twice daily. Each 10mg vial dissolves into 1-3mL of water-based or hyaluronic-acid serum base. Visible smoothing effects typically appear at 4-6 weeks of consistent application.
How is SNAP-8 tested?
Each SNAP-8 lot is HPLC-tested to ≥99% purity, confirmed by ESI mass spectrometry against the theoretical 888.0 Da molecular weight, and LAL endotoxin tested. ISO 17025-accredited third-party labs perform the testing.
How do I store SNAP-8?
Lyophilized SNAP-8 is stable at -20°C for 24+ months. Once dissolved into a topical base, store refrigerated and use within 60 days for best stability.