Support & Solvents
Injection Kit
50 syringes + 100 padsEverything required to safely reconstitute and inject reconstituted peptides — 50 sterile insulin syringes plus 100 alcohol prep pads.
$25
Lyophilized · 10 mg / vial
Growth & Anabolic
10 mg / vial
MOTS-c 10mg — Mitochondrial-Derived Peptide
16-amino-acid mitochondrial ORF peptide · AMPK signaling · Insulin sensitivity
Premium Grade
Mitochondrial-derived 16-amino acid peptide — endogenous regulator of insulin sensitivity and metabolic homeostasis.
- CAS Number
- 1627580-64-6
- Molecular Weight
- 2 174.6 Da
- Purity
- ≥ 99.0% (HPLC)
- Storage
- −20 °C, lyophilized
Amino Acid Sequence
MRWQEMGYIFYPRKLR
Free over $59$7.99 to US (48h) · $14.99 worldwide (5 business days)
Discreet PackagingPlain insulated mailer, no compound name on the outside.
Certificate of Analysis
Per-lot analytical report — HPLC, ESI-MS, LAL endotoxin, heavy metals, sterility
Current lotMOT533
Released2026-04-15
HPLC purity99.86%
Endotoxin (LAL)Pass · < 0.5 EU/mg
About MOTS-c
Buy MOTS-c 10mg at IGF1 Shop. MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded by the mitochondrial genome. It targets the muscle-mitochondria axis, modulating AMPK signaling and improving insulin sensitivity and exercise capacity. Each MOTS-c 10mg vial is HPLC-verified at ≥99% purity with a per-lot Certificate of Analysis, ESI mass-spec confirmation, and LAL endotoxin testing below 0.5 EU/mg.
Also known as: MOTS-c · Mitochondrial-derived peptide · MOTSc · MORF peptide
MOTS-c — Mechanism & Specifications
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded by the mitochondrial genome. It targets the muscle-mitochondria axis, modulating AMPK signaling and improving insulin sensitivity and exercise capacity.
Quality & release criteria
Every lot of MOTS-c is released only after passing reverse-phase HPLC (≥ 99% area purity at 220 nm against a reference standard), ESI mass spectrometry confirmation of molecular weight, and Limulus Amebocyte Lysate (LAL) endotoxin testing below 0.5 EU/mg. The lot-specific Certificate of Analysis is provided with the order and available on request before purchase.
$66
3 vials · $22/vial
FAQ
MOTS-c — Frequently asked questions
What is MOTS-c?
MOTS-c is a 16-amino-acid peptide encoded by the mitochondrial 12S rRNA gene — one of the first identified mitochondrial-derived peptides. Its sequence (MRWQEMGYIFYPRKLR) targets the AMPK signaling pathway, modulating energy metabolism and insulin sensitivity. CAS 1627580-64-6.
What is the typical MOTS-c dose?
Common protocols use 5-10 mg per week, split into 2-3 subcutaneous injections. A 10mg vial reconstituted with 2mL bacteriostatic water yields 5mg per mL — a 0.1mL injection delivers 500 mcg. Typical cycle length is 4-12 weeks followed by a break.
How is MOTS-c stored?
Lyophilized MOTS-c is stable at -20°C for 24+ months. After reconstitution with bacteriostatic water, store refrigerated at 2-8°C and use within 30 days. Protect from light and avoid freeze-thaw cycles on the reconstituted solution.
How is your MOTS-c tested?
Each MOTS-c lot is HPLC-tested to ≥99% purity, confirmed by ESI mass spectrometry against the theoretical 2,174.6 Da molecular weight, and LAL endotoxin tested below 0.5 EU/mg. Testing is performed by ISO 17025-accredited third-party labs. The per-lot COA accompanies every shipment.
Do you ship MOTS-c internationally?
Yes — MOTS-c ships worldwide in plain, unbranded discreet packaging with tracked delivery. Orders over $59 ship free. We accept Bitcoin, USDT, Ethereum, Monero, Litecoin, and major cards.
