Support & Solvents
Injection Kit
50 syringes + 100 padsEverything required to safely reconstitute and inject reconstituted peptides — 50 sterile insulin syringes plus 100 alcohol prep pads.
$25
Lyophilized · 10 mg / vial
Skin & Cosmetic
10 mg / vial
Melanotan II (MT-2) 10mg — Cyclic α-MSH Analog
Non-selective melanocortin agonist · MC1R/3R/4R/5R · Tanning + libido pathways
Premium Grade
Bestseller
Cyclic synthetic analog of α-MSH — non-selective melanocortin receptor agonist with potent melanogenic and libido-modulating activity.
- CAS Number
- 121062-08-6
- Molecular Weight
- 1 024.18 Da
- Purity
- ≥ 99.0% (HPLC)
- Storage
- −20 °C, lyophilized
Amino Acid Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Free over $59$7.99 to US (48h) · $14.99 worldwide (5 business days)
Discreet PackagingPlain insulated mailer, no compound name on the outside.
Certificate of Analysis
Per-lot analytical report — HPLC, ESI-MS, LAL endotoxin, heavy metals, sterility
Current lotMEL577
Released2026-04-12
HPLC purity99.19%
Endotoxin (LAL)Pass · < 0.5 EU/mg
About Melanotan II (MT-2)
Buy Melanotan 2 (MT-2) 10mg at IGF1 Shop. Melanotan II — also written MT-2 or MT-II — is a cyclic synthetic analog of α-melanocyte-stimulating hormone (α-MSH), originally developed at the University of Arizona. It is a non-selective agonist at the melanocortin receptors MC1R, MC3R, MC4R, and MC5R. Activation of MC1R on melanocytes drives eumelanin production, which is what creates the deep, lasting tan associated with Melanotan II. Each MT-2 10mg vial is HPLC ≥99% pure, identity-confirmed by ESI mass-spec against the theoretical 1,024.18 Da molecular weight, and accompanied by a per-lot Certificate of Analysis. CAS 121062-08-6.
Also known as: Melanotan 2 · Melanotan II · MT-2 · MT-II · MT2 · Melanotan-II
Melanotan II (MT-2) — Mechanism & Specifications
Melanotan II is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone, originally developed at the University of Arizona as a sunless-tanning compound. It activates MC1R (melanogenesis), MC3R, MC4R and MC5R, producing both pigmentation and behavioral effects.
Quality & release criteria
Every lot of Melanotan II (MT-2) is released only after passing reverse-phase HPLC (≥ 99% area purity at 220 nm against a reference standard), ESI mass spectrometry confirmation of molecular weight, and Limulus Amebocyte Lysate (LAL) endotoxin testing below 0.5 EU/mg. The lot-specific Certificate of Analysis is provided with the order and available on request before purchase.
$54
3 vials · $18/vial
FAQ
Melanotan II (MT-2) — Frequently asked questions
What is Melanotan II?
Melanotan II, also written MT-2 or MT-II, is a cyclic synthetic analog of α-MSH (alpha-melanocyte-stimulating hormone). It is a non-selective agonist at the melanocortin receptors MC1R, MC3R, MC4R, and MC5R. Activation of MC1R on melanocytes drives eumelanin production, which is what creates the deep, lasting tan associated with this peptide.
What is the standard Melanotan II tanning protocol?
A typical loading phase is 0.25-0.5mg per day subcutaneously for 10-20 days, paired with brief, controlled UV exposure 2-3 times per week. Once your target shade is reached, maintenance is usually 0.5-1mg total per week, split into 1-2 injections. Fair-skin users (Fitzpatrick I-II) should start at 0.1-0.25mg to gauge tolerance.
How fast does Melanotan II work?
Initial freckling or subtle darkening typically appears within 2-3 days of starting a loading dose. Visible color depth emerges around day 7-10, and full melanin saturation is reached at 2-3 weeks of combined dosing and UV exposure. Without any UV exposure, the tan develops more slowly and unevenly.
How do I reconstitute and dose a 10mg MT-2 vial?
Add 1mL of bacteriostatic water down the side of the Melanotan II vial — do not shake, just swirl. At 1mL dilution, 0.05mL (5 units on a U-100 insulin syringe) delivers 0.5mg. Reconstituted vials are stable refrigerated at 2-8°C for roughly 30 days; lyophilized vials are stable at -20°C for two years.
What side effects are common with MT-2?
The most frequently reported are mild nausea and facial flushing during the first 2-3 injections of the loading phase, usually fading as tolerance builds. Appetite suppression is common — many users drop 1-3 kg without intending to. Spontaneous erections in males and darkening of existing moles or freckles are also commonly reported.
What purity and testing does the Melanotan II vial carry?
Every lot of Melanotan II is HPLC-tested to ≥99% purity, identity-confirmed by ESI mass spectrometry against the C50H69N15O9 reference (MW 1024.18, CAS 121062-08-6), and endotoxin-tested by LAL to <0.5 EU/mg. The per-lot Certificate of Analysis is issued by an ISO 17025-accredited laboratory.
How is Melanotan II shipped and what payments are accepted?
All Melanotan II packaging is plain, discreet, and unmarked. Orders over $59 within the US ship free; international shipping is available worldwide with full tracking. Bitcoin, USDT, Ethereum, Monero, Litecoin, and major cards are accepted, with a small crypto discount applied at checkout.
