Support & Solvents
Injection Kit
50 syringes + 100 padsEverything required to safely reconstitute and inject reconstituted peptides — 50 sterile insulin syringes plus 100 alcohol prep pads.
$25
Lyophilized · 10 mg / vial
Skin & Cosmetic
10 mg / vial
Melanotan I (MT-1, Afamelanotide) 10mg
Linear α-MSH analog · Selective MC1R · Cleaner melanogenesis profile
Premium Grade
Linear synthetic α-MSH analog — selective MC1R activation for melanogenesis without significant libido-pathway effects.
- CAS Number
- 75921-69-6
- Molecular Weight
- 1 646.85 Da
- Purity
- ≥ 99.0% (HPLC)
- Storage
- −20 °C, lyophilized
Amino Acid Sequence
Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Free over $59$7.99 to US (48h) · $14.99 worldwide (5 business days)
Discreet PackagingPlain insulated mailer, no compound name on the outside.
Certificate of Analysis
Per-lot analytical report — HPLC, ESI-MS, LAL endotoxin, heavy metals, sterility
Current lotMEL107
Released2026-04-24
HPLC purity99.21%
Endotoxin (LAL)Pass · < 0.5 EU/mg
About Melanotan I (MT-1, Afamelanotide)
Buy Melanotan I (MT-1, Afamelanotide) 10mg at IGF1 Shop. Melanotan I is a 13-amino-acid linear analog of α-MSH with Nle⁴ and D-Phe⁷ substitutions. Unlike Melanotan II, Melanotan I is not cyclized, which confers greater MC1R receptor selectivity and a cleaner profile for users focused purely on melanogenesis (tanning) without significant libido-pathway side effects. Each Melanotan I 10mg vial is HPLC-verified at ≥99% purity, ESI mass-spec confirmed against the theoretical 1,646.85 Da molecular weight, and shipped with a per-lot Certificate of Analysis. CAS 75921-69-6.
Also known as: Melanotan I · Melanotan 1 · MT-1 · MT-I · Afamelanotide
Melanotan I (MT-1, Afamelanotide) — Mechanism & Specifications
Melanotan I (Afamelanotide) is a 13-amino acid linear analog of α-MSH with a Nle⁴ and D-Phe⁷ substitution. Unlike MT-2, it is not cyclized, conferring greater MC1R selectivity and a cleaner profile for melanogenesis-focused use.
Quality & release criteria
Every lot of Melanotan I (MT-1, Afamelanotide) is released only after passing reverse-phase HPLC (≥ 99% area purity at 220 nm against a reference standard), ESI mass spectrometry confirmation of molecular weight, and Limulus Amebocyte Lysate (LAL) endotoxin testing below 0.5 EU/mg. The lot-specific Certificate of Analysis is provided with the order and available on request before purchase.
$54
3 vials · $18/vial
FAQ
Melanotan I (MT-1, Afamelanotide) — Frequently asked questions
What is Melanotan I?
Melanotan I (Afamelanotide) is a 13-amino-acid linear analog of α-MSH with Nle⁴ and D-Phe⁷ substitutions. Unlike Melanotan II, it is not cyclized, conferring greater MC1R selectivity and a cleaner profile for melanogenesis-focused use. CAS 75921-69-6.
How is Melanotan I different from Melanotan II?
Melanotan I (linear) is selective for MC1R, the receptor responsible for melanogenesis (tanning). Melanotan II (cyclic) activates MC1R, MC3R, MC4R, and MC5R — meaning it produces tanning plus appetite suppression, libido effects, and other off-target effects. Choose MT-1 if you want a tan without the systemic effects; choose MT-2 if you want the combined profile.
What is the typical Melanotan I dose?
Common protocols use 0.5-1mg per day subcutaneously during a loading phase of 10-20 days, then maintenance dosing of 1mg 1-2 times per week with UV exposure. Each 10mg vial reconstituted with 1mL bacteriostatic water yields 1mg per 0.1mL.
How is Melanotan I tested?
Each Melanotan I lot is HPLC-tested to ≥99% purity, confirmed by ESI mass spectrometry, and LAL endotoxin tested below 0.5 EU/mg. ISO 17025-accredited third-party labs perform the testing; the per-lot COA accompanies every shipment.
How do I store Melanotan I?
Lyophilized Melanotan I is stable at -20°C for 24+ months. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Protect from light.
