Support & Solvents
Injection Kit
50 syringes + 100 padsEverything required to safely reconstitute and inject reconstituted peptides — 50 sterile insulin syringes plus 100 alcohol prep pads.
$25
Lyophilized · 1 mg / vial
Growth & Anabolic
1 mg / vial
IGF-1 LR3 1mg — Receptor Grade Long R3 IGF-1
Long-Arg3 Insulin-like Growth Factor · 83-AA · Extended half-life via reduced IGFBP affinity
Premium Grade
HPLC Certified
Long-Arg3 Insulin-like Growth Factor — modified IGF-1 analog with significantly extended half-life via reduced IGFBP affinity.
- CAS Number
- 946870-92-4
- Molecular Weight
- 9 117 Da
- Purity
- ≥ 99.0% (HPLC)
- Storage
- −20 °C, lyophilized
Amino Acid Sequence
MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA
Free over $59$7.99 to US (48h) · $14.99 worldwide (5 business days)
Discreet PackagingPlain insulated mailer, no compound name on the outside.
Certificate of Analysis
Per-lot analytical report — HPLC, ESI-MS, LAL endotoxin, heavy metals, sterility
Current lotIGF246
Released2026-04-28
HPLC purity99.65%
Endotoxin (LAL)Pass · < 0.5 EU/mg
About IGF-1 LR3
Buy IGF-1 LR3 1mg vials at IGF1 Shop. Our IGF-1 LR3 is supplied as a lyophilized white powder at ≥99% HPLC purity, with every batch confirmed by ESI mass spectrometry and tested for endotoxins below 0.5 EU/mg. IGF-1 LR3 (Long-Arg3 Insulin-like Growth Factor-1) is an 83-amino-acid analog of human IGF-1 with both a 13-residue N-terminal extension and an arginine substitution at position 3 — modifications that dramatically reduce binding to IGF-binding proteins and extend the serum half-life from roughly 10 minutes for native IGF-1 to 20-30 hours for IGF-1 LR3. Receptor Grade indicates the peptide retains full binding affinity at the IGF-1 receptor, verified by mass-spec rather than just gross purity.
Also known as: Long R3 IGF-1 · IGF-1 LR3 · IGF1 LR3 · Receptor Grade IGF-1 LR3
IGF-1 LR3 — Mechanism & Specifications
IGF-1 LR3 is an 83-amino-acid analog of human IGF-1 with a 13-amino-acid N-terminal extension and an arginine substitution at position 3. Both modifications dramatically reduce binding to IGF-binding proteins, increasing free serum availability and biological half-life from 10 minutes (native IGF-1) to over 6 hours.
Quality & release criteria
Every lot of IGF-1 LR3 is released only after passing reverse-phase HPLC (≥ 99% area purity at 220 nm against a reference standard), ESI mass spectrometry confirmation of molecular weight, and Limulus Amebocyte Lysate (LAL) endotoxin testing below 0.5 EU/mg. The lot-specific Certificate of Analysis is provided with the order and available on request before purchase.
$126
3 vials · $42/vial
FAQ
IGF-1 LR3 — Frequently asked questions
What is IGF-1 LR3 and how is it different from regular IGF-1?
IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is an 83-amino-acid analog of human IGF-1 with an arginine-substituted N-terminus extension. The modifications make it roughly three times more active than native IGF-1 and extend the half-life from ~10 minutes to ~20-30 hours by preventing binding to IGF binding proteins. Each IGF1 Shop 1mg vial is supplied as a lyophilized powder at ≥99% HPLC purity.
What does "Receptor Grade" IGF-1 LR3 mean?
Receptor Grade indicates the peptide retains full binding affinity at the IGF-1 receptor, verified by mass-spec and HPLC profiling rather than just gross purity. It is the standard term used by top peptide suppliers to distinguish a correctly folded, biologically active LR3 analog from underactive or misfolded batches. Every IGF-1 LR3 lot we ship is mass-spec confirmed against the theoretical molecular weight.
How do I reconstitute a 1mg vial of IGF-1 LR3?
Add 1 mL of bacteriostatic water to the vial for a working concentration of 1 mg/mL (1000 mcg/mL) — every 0.05 mL (5 units on a U-100 insulin syringe) then delivers 50 mcg of IGF-1 LR3. Swirl gently; never shake. Store the reconstituted vial refrigerated at 2-8 °C and use within 14-21 days for best stability.
How long does one 1mg vial of IGF-1 LR3 last?
At a common 40 mcg daily dose, one 1mg IGF-1 LR3 vial covers 25 days. At 50 mcg, it covers 20 days. At 80 mcg, it covers 12-13 days. Most users run 4-week cycles, so 1-2 vials per cycle is typical.
How is your IGF-1 LR3 tested?
Every batch is verified by HPLC for purity (≥99%), ESI mass spectrometry for molecular identity (target MW ~9117 Da), and LAL assay for endotoxin (<0.5 EU/mg). Testing is performed by ISO 17025-accredited third-party labs. A per-lot Certificate of Analysis is published on the product page and included with the shipment.
How should IGF-1 LR3 be stored?
Lyophilized IGF-1 LR3 is best stored frozen at -20 °C for long-term stability and is stable refrigerated at 2-8 °C for shorter periods. Protect from light and freeze-thaw cycles. After reconstitution with bacteriostatic water, refrigerate and use within 14-21 days; do not freeze the reconstituted solution.
How does IGF-1 LR3 compare to IGF-1 DES and MGF?
IGF-1 LR3 has the longest half-life of the three (~20-30 hours) and acts systemically. IGF-1 DES is a truncated analog with very short half-life (~30 minutes) typically used for localized, site-specific effects. MGF (Mechano Growth Factor) is a splice variant released after muscle damage and acts locally on satellite cells. The three are often discussed together because they target overlapping pathways via different kinetics.
Do you ship IGF-1 LR3 internationally and discreetly?
Yes — we ship IGF-1 LR3 worldwide in plain, unbranded packaging with no peptide-related markings on the outer label. Lyophilized vials are stable at ambient temperatures for transit. Tracked delivery from dispatch to door. Domestic orders typically arrive in 2-5 business days; international 7-14. Free shipping applies on orders over $59.
