冻干 · 10 mg / vial 3-GLP (Retatrutide) 10 mg / vial — 经 HPLC 验证的多肽瓶

代谢与体重 10 mg / vial

Retatrutide 10mg (3-GLP) — Triple GLP-1 / GIP / Glucagon Agonist

Q: What is Retatrutide (3-GLP)?

Retatrutide, also known as 3-GLP or LY3437943, is a synthetic peptide that activates three metabolic receptors simultaneously: GLP-1, GIP, and glucagon. This triple-agonist design is what sets it apart from single-agonist Semaglutide and dual-agonist Tirzepatide. Each IGF1 Shop vial contains 10mg of lyophilized Retatrutide acetate, HPLC-verified at ≥99% purity. CAS 2381089-83-2.

Q: What is the typical Retatrutide dose?

The standard Retatrutide titration starts at 2mg once weekly and escalates every 4 weeks: 2mg → 4mg → 8mg → 12mg. Most users reach a maintenance dose between 8mg and 12mg weekly. One 10mg vial reconstituted with 2mL of bacteriostatic water yields 5mg per mL — a 0.4mL injection delivers a 2mg dose, 0.8mL delivers 4mg.

Q: How much weight loss is reported with Retatrutide?

In Eli Lilly's Phase 2 trial published in NEJM, participants on 8mg and 12mg weekly lost an average of 22.8% and 24.2% of body weight over 48 weeks. The Phase 3 TRIUMPH-4 readout reported up to 28.7% mean weight reduction (about 71 lbs) at 68 weeks. Retatrutide currently produces the largest weight-loss numbers of any GLP-class compound.

Q: How do I reconstitute a 10mg Retatrutide vial?

Inject 2mL of bacteriostatic water slowly down the side of the Retatrutide vial; do not shake — swirl gently until clear. The reconstituted solution contains 5mg per mL. Store reconstituted vials refrigerated at 2-8°C and use within 30 days. Lyophilized vials are stable for 24 months at -20°C.

Q: How is IGF1 Shop's Retatrutide quality verified?

Every Retatrutide lot is tested by ISO 17025 third-party labs and ships with a downloadable Certificate of Analysis matched to your vial's batch number. Tests include reverse-phase HPLC for purity (≥99%), ESI mass spectrometry for molecular weight confirmation, and LAL assay for bacterial endotoxins (<0.5 EU/mg).

Q: How does Retatrutide compare to Tirzepatide and Semaglutide?

Semaglutide hits one receptor (GLP-1). Tirzepatide hits two (GLP-1 + GIP). Retatrutide hits three (GLP-1 + GIP + glucagon). Adding the glucagon receptor drives additional fat oxidation and resting energy expenditure, which is the proposed mechanism behind Retatrutide's larger weight-loss numbers in head-to-head trial data.

Q: How is Retatrutide shipped and packaged?

Retatrutide vials ship in temperature-stable, discreet packaging worldwide. Orders over $59 ship free. Domestic US orders typically arrive in 2-4 business days; international 7-14 days. We accept Bitcoin, Ethereum, USDT, Monero, Litecoin, and major cards. Tracking is provided on every order.

Q: What is the shelf life of Retatrutide?

Unopened lyophilized Retatrutide vials kept at -20°C are stable for 24 months from the lot date printed on the label. At room temperature, lyophilized vials remain stable for up to 30 days. Once reconstituted with bacteriostatic water, store at 2-8°C and use within 30 days for full potency.

39-AA triple agonist · LY3437943 · ~6-day half-life · Aib-substituted, C20 fatty-diacid

Premium Grade 高需求

First-in-class triple agonist of GIP, GLP-1 and glucagon receptors — extended half-life via fatty-acid acylation.

CAS 编号: 2381089-83-2
分子量: 4 731.4 Da
纯度: ≥ 99.0% (HPLC)
储存: −20 °C，冻干

氨基酸序列 GIP / GLP-1 / Glucagon triple receptor agonist — 39 AA synthetic peptide with α-aminoisobutyric acid (Aib) substitutions and a γGlu-spacer C20 eicosanedioic-acid moiety at Lys17

选择您的套装

1 瓶 $67 /瓶 $67 总计最受欢迎 3 瓶 $47 /瓶 $141 总计最高性价比 10 瓶 $34 /瓶 $340 总计

订单满 $59 免费$7.99 美国境内（48小时）· $14.99 全球（5个工作日）

低调包装普通隔热邮袋，外包装不显示化合物名称。

分析证书

每批次分析报告 — HPLC、ESI-MS、LAL 内毒素检测、重金属、无菌性

当前批次GLP694

已放行2026-04-21

HPLC 纯度99.45%

内毒素（LAL）通过 · < 0.5 EU/mg

阅读完整 COA 查看所有实验室结果

关于 3-GLP (Retatrutide)

Buy Retatrutide 10mg at IGF1 Shop. Retatrutide, also known as 3-GLP or LY3437943, is a first-in-class synthetic 39-amino-acid peptide that simultaneously activates three metabolic receptors: GLP-1, GIP, and glucagon. This triple-agonist design is what sets Retatrutide apart from single-agonist Semaglutide and dual-agonist Tirzepatide. Strategic α-aminoisobutyric acid (Aib) substitutions confer protease resistance, and a C20 fatty diacid attached via γGlu-spacer at Lys17 produces high-affinity albumin binding with a serum half-life of approximately 6 days. Each Retatrutide 10mg vial is HPLC-verified at ≥99% purity, ESI mass-spec confirmed against the theoretical 4,731.4 Da molecular weight, and accompanied by a per-lot Certificate of Analysis. CAS 2381089-83-2.

又称： Retatrutide · 3-GLP · LY3437943 · Triple agonist peptide

3-GLP (Retatrutide) — 作用机制与规格

Retatrutide (LY3437943, project name 3-GLP) is a 39-amino acid synthetic peptide engineered as a single-molecule agonist of three incretin and metabolic receptors simultaneously. Strategic α-aminoisobutyric acid substitutions confer protease resistance, and a C20 fatty diacid attached via γGlu-spacer at Lys17 produces high-affinity albumin binding with a serum half-life of ~6 days.

质量与放行标准

3-GLP (Retatrutide) 的每批次仅在通过反相 HPLC（220 nm 下对照参考标准品面积纯度 ≥ 99%）、ESI 质谱分子量确认及鲎变形细胞溶解物（LAL）内毒素检测（低于 0.5 EU/mg）后才予以放行。批次专属分析证书随订单提供，购买前可按需索取。

常见问题

3-GLP (Retatrutide) — 常见问题

What is Retatrutide (3-GLP)?

Retatrutide, also known as 3-GLP or LY3437943, is a synthetic peptide that activates three metabolic receptors simultaneously: GLP-1, GIP, and glucagon. This triple-agonist design is what sets it apart from single-agonist Semaglutide and dual-agonist Tirzepatide. Each IGF1 Shop vial contains 10mg of lyophilized Retatrutide acetate, HPLC-verified at ≥99% purity. CAS 2381089-83-2.

What is the typical Retatrutide dose?

The standard Retatrutide titration starts at 2mg once weekly and escalates every 4 weeks: 2mg → 4mg → 8mg → 12mg. Most users reach a maintenance dose between 8mg and 12mg weekly. One 10mg vial reconstituted with 2mL of bacteriostatic water yields 5mg per mL — a 0.4mL injection delivers a 2mg dose, 0.8mL delivers 4mg.

How much weight loss is reported with Retatrutide?

In Eli Lilly's Phase 2 trial published in NEJM, participants on 8mg and 12mg weekly lost an average of 22.8% and 24.2% of body weight over 48 weeks. The Phase 3 TRIUMPH-4 readout reported up to 28.7% mean weight reduction (about 71 lbs) at 68 weeks. Retatrutide currently produces the largest weight-loss numbers of any GLP-class compound.

How do I reconstitute a 10mg Retatrutide vial?

Inject 2mL of bacteriostatic water slowly down the side of the Retatrutide vial; do not shake — swirl gently until clear. The reconstituted solution contains 5mg per mL. Store reconstituted vials refrigerated at 2-8°C and use within 30 days. Lyophilized vials are stable for 24 months at -20°C.

How is IGF1 Shop's Retatrutide quality verified?

Every Retatrutide lot is tested by ISO 17025 third-party labs and ships with a downloadable Certificate of Analysis matched to your vial's batch number. Tests include reverse-phase HPLC for purity (≥99%), ESI mass spectrometry for molecular weight confirmation, and LAL assay for bacterial endotoxins (<0.5 EU/mg).

How does Retatrutide compare to Tirzepatide and Semaglutide?

Semaglutide hits one receptor (GLP-1). Tirzepatide hits two (GLP-1 + GIP). Retatrutide hits three (GLP-1 + GIP + glucagon). Adding the glucagon receptor drives additional fat oxidation and resting energy expenditure, which is the proposed mechanism behind Retatrutide's larger weight-loss numbers in head-to-head trial data.

How is Retatrutide shipped and packaged?

Retatrutide vials ship in temperature-stable, discreet packaging worldwide. Orders over $59 ship free. Domestic US orders typically arrive in 2-4 business days; international 7-14 days. We accept Bitcoin, Ethereum, USDT, Monero, Litecoin, and major cards. Tracking is provided on every order.

What is the shelf life of Retatrutide?