Support & Solvents
Injection Kit
50 syringes + 100 padsEverything required to safely reconstitute and inject reconstituted peptides — 50 sterile insulin syringes plus 100 alcohol prep pads.
$25
Лиофилизированный · 10 mg / vial
Метаболизм и масса тела
10 mg / vial
Retatrutide 10mg (3-GLP) — Triple GLP-1 / GIP / Glucagon Agonist
39-AA triple agonist · LY3437943 · ~6-day half-life · Aib-substituted, C20 fatty-diacid
Premium Grade
Высокий спрос
First-in-class triple agonist of GIP, GLP-1 and glucagon receptors — extended half-life via fatty-acid acylation.
- Номер CAS
- 2381089-83-2
- Молекулярная масса
- 4 731.4 Da
- Чистота
- ≥ 99.0% (HPLC)
- Хранение
- −20 °C, лиофилизированный
Аминокислотная последовательность
GIP / GLP-1 / Glucagon triple receptor agonist — 39 AA synthetic peptide with α-aminoisobutyric acid (Aib) substitutions and a γGlu-spacer C20 eicosanedioic-acid moiety at Lys17
Бесплатно при заказе от USD$7.99 по США (48 ч) · $14.99 по всему миру (5 рабочих дней)
Конфиденциальная упаковкаПростой теплоизолированный конверт, без названия соединения снаружи.
Сертификат анализа
Аналитический отчёт на серию — HPLC, ESI-MS, LAL-эндотоксин, тяжёлые металлы, стерильность
Текущая партияGLP694
Выпущено2026-04-21
Чистота по HPLC99.45%
Эндотоксин (LAL)Пройдено · < 0.5 EU/mg
О 3-GLP (Retatrutide)
Buy Retatrutide 10mg at IGF1 Shop. Retatrutide, also known as 3-GLP or LY3437943, is a first-in-class synthetic 39-amino-acid peptide that simultaneously activates three metabolic receptors: GLP-1, GIP, and glucagon. This triple-agonist design is what sets Retatrutide apart from single-agonist Semaglutide and dual-agonist Tirzepatide. Strategic α-aminoisobutyric acid (Aib) substitutions confer protease resistance, and a C20 fatty diacid attached via γGlu-spacer at Lys17 produces high-affinity albumin binding with a serum half-life of approximately 6 days. Each Retatrutide 10mg vial is HPLC-verified at ≥99% purity, ESI mass-spec confirmed against the theoretical 4,731.4 Da molecular weight, and accompanied by a per-lot Certificate of Analysis. CAS 2381089-83-2.
Также известно как: Retatrutide · 3-GLP · LY3437943 · Triple agonist peptide
3-GLP (Retatrutide) — Механизм действия и технические характеристики
Retatrutide (LY3437943, project name 3-GLP) is a 39-amino acid synthetic peptide engineered as a single-molecule agonist of three incretin and metabolic receptors simultaneously. Strategic α-aminoisobutyric acid substitutions confer protease resistance, and a C20 fatty diacid attached via γGlu-spacer at Lys17 produces high-affinity albumin binding with a serum half-life of ~6 days.
Качество и критерии выпуска
Каждая партия 3-GLP (Retatrutide) выпускается только после прохождения ВЭЖХ с обращённой фазой (≥ 99% чистоты по площади при 220 nm относительно референтного стандарта), подтверждения молекулярной массы методом ESI масс-спектрометрии и тестирования на эндотоксины лизатом амёбоцитов Limulus (LAL) ниже 0,5 EU/mg. Сертификат анализа для конкретной партии прилагается к заказу и предоставляется по запросу до совершения покупки.
$141
3 флаконы · $47/флакон
Часто задаваемые вопросы
3-GLP (Retatrutide) — Часто задаваемые вопросы
What is Retatrutide (3-GLP)?
Retatrutide, also known as 3-GLP or LY3437943, is a synthetic peptide that activates three metabolic receptors simultaneously: GLP-1, GIP, and glucagon. This triple-agonist design is what sets it apart from single-agonist Semaglutide and dual-agonist Tirzepatide. Each IGF1 Shop vial contains 10mg of lyophilized Retatrutide acetate, HPLC-verified at ≥99% purity. CAS 2381089-83-2.
What is the typical Retatrutide dose?
The standard Retatrutide titration starts at 2mg once weekly and escalates every 4 weeks: 2mg → 4mg → 8mg → 12mg. Most users reach a maintenance dose between 8mg and 12mg weekly. One 10mg vial reconstituted with 2mL of bacteriostatic water yields 5mg per mL — a 0.4mL injection delivers a 2mg dose, 0.8mL delivers 4mg.
How much weight loss is reported with Retatrutide?
In Eli Lilly's Phase 2 trial published in NEJM, participants on 8mg and 12mg weekly lost an average of 22.8% and 24.2% of body weight over 48 weeks. The Phase 3 TRIUMPH-4 readout reported up to 28.7% mean weight reduction (about 71 lbs) at 68 weeks. Retatrutide currently produces the largest weight-loss numbers of any GLP-class compound.
How do I reconstitute a 10mg Retatrutide vial?
Inject 2mL of bacteriostatic water slowly down the side of the Retatrutide vial; do not shake — swirl gently until clear. The reconstituted solution contains 5mg per mL. Store reconstituted vials refrigerated at 2-8°C and use within 30 days. Lyophilized vials are stable for 24 months at -20°C.
How is IGF1 Shop's Retatrutide quality verified?
Every Retatrutide lot is tested by ISO 17025 third-party labs and ships with a downloadable Certificate of Analysis matched to your vial's batch number. Tests include reverse-phase HPLC for purity (≥99%), ESI mass spectrometry for molecular weight confirmation, and LAL assay for bacterial endotoxins (<0.5 EU/mg).
How does Retatrutide compare to Tirzepatide and Semaglutide?
Semaglutide hits one receptor (GLP-1). Tirzepatide hits two (GLP-1 + GIP). Retatrutide hits three (GLP-1 + GIP + glucagon). Adding the glucagon receptor drives additional fat oxidation and resting energy expenditure, which is the proposed mechanism behind Retatrutide's larger weight-loss numbers in head-to-head trial data.
How is Retatrutide shipped and packaged?
Retatrutide vials ship in temperature-stable, discreet packaging worldwide. Orders over $59 ship free. Domestic US orders typically arrive in 2-4 business days; international 7-14 days. We accept Bitcoin, Ethereum, USDT, Monero, Litecoin, and major cards. Tracking is provided on every order.
What is the shelf life of Retatrutide?
Unopened lyophilized Retatrutide vials kept at -20°C are stable for 24 months from the lot date printed on the label. At room temperature, lyophilized vials remain stable for up to 30 days. Once reconstituted with bacteriostatic water, store at 2-8°C and use within 30 days for full potency.
